The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Clinical Roundup

USPSTF issues draft recommendation statement on screening for cervical cancer

Lynparza demonstrates survival benefit in early breast cancer, phase III trial data show

Imlunestrant improves PFS in breast cancer, phase III data show

Phase III trial shows improved PFS in treatment of CLL using pirtobrutinib

AI test is equivalent to Oncotype DX at predicting breast cancer recurrence, study shows

MammaPrint test demonstrates utility in predicting chemotherapy benefit over five years

Genetic disposition increases the risk of breast cancer metastasis

Kisqali shows reduction in distant recurrence in early breast cancer, phase III data show

Darzalex Faspro-based regimens demonstrate improved rates of MRD negativity and PFS

Nektar Therapeutics announces NKTR-255 enhanced complete response rates in r/r LBCL

Yescarta demonstrates improved outcomes for r/r LBCL

Calquence + Venetoclax shows superior PFS in untreated CLL in AMPLIFY phase III trial

Tecvayli demonstrates potential in MM

Blenrep combination shows OS benefit in MM

Antibody shows encouraging results for treating high-risk follicular lymphoma and marginal zone lymphoma

Carvykti demonstrates higher rates of MRD negativity, phase III study shows

Genetic mutations accumulate in smokers with MDS, study shows

High-dose chemo + autologous stem cell therapy demonstrates no benefit in MRD-negative mantle-cell lymphoma, phase III study shows

Phase II OVATION 2 Study of IMNN-001 shows positive OS for ovarian cancer

Hair growth drug safe at low doses for breast cancer patients

Monoclonal antibody improves survival in cancer-associated hyper-inflammatory disorder

HIFU demonstrates positive outcomes in management of prostate cancer, study shows

“Biological age” may predict early colorectal cancer risk

Repurposed drug has promising efficacy in shrinking NSCLC tumors

Blood test predicts prognosis for advanced prostate cancer, study finds

Study identifies that higher West African ancestry may contribute to worse outcomes

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