The Cancer Letter

Inside information on cancer research and drug development

ACT for NIH publishes Mary Lasker biography to use in lobbying for appropriations—Mary would’ve approved

In Brief

Patricia M. LoRusso elected AACR president-elect for 2023-2024
ACS receives $4M from Genentech to drive health equity
Stephen Klasko and Colleen Wyse to fund a ACS research program to improve access to quality care
Crystal Mackall to receive the Edward Netter Leadership Award for cancer immunotherapy contributions
ACCC releases 2022 Impact Report
Florencia McAllister to receive TAMEST Mary Beth Maddox Award for pancreatic tumor microbiome research

Drugs & Targets

FDA releases draft guidance aimed at improving oncology clinical trials for accelerated approval
FDA grants accelerated approval to Zynyz for metastatic or recurrent locally advanced Merkel cell carcinoma
ACS & Winship Cancer Institute partner to accelerate cancer research in Georgia
FDA approves Tafinlar + Mekinist for pediatric patients with low-grade glioma with a BRAF V600E mutation
Prelude Therapeutics to collaborate with BeiGene to evaluate PRT2527 + zanubrutinib in hematologic cancers
FDA broadens indication for Verzenio in HR+, HER2-, node-positive, high-risk early breast cancer

In The Clinic

Trials & Tribulations

Does salpingectomy prevent ovarian cancer? Let’s prove it.
The SOROCk clinical trial, NRG CC008 (NCT04251052)

Does salpingectomy prevent ovarian cancer? Let’s prove it. The SOROCk clinical trial, NRG CC008 (NCT04251052)
Cancer patients have sevenfold suicide risk in first six months after diagnosis The SOROCk clinical trial, NRG CC008 (NCT04251052)
Grant-funded, investigator-initiated trials fail to bounce back from COVID as 50% of research staff left for higher-paying jobs
MRI-guided radiotherapy for prostate cancer: Lessons from the MIRAGE trial
Trials & Tribulations
Ignore at your own risk: FDA draft guidance puts flashing lights around “dose optimization”
FreeTrials & Tribulations

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UPCOMING EVENTS

May 2023
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The 6th International Molecular Pathological Epidemiology (MPE) Meeting: 10-Year Anniversary Summit
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The Cancer Letter is an independent weekly news publication and the leading source for information on the issues that shape oncology.

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