The Cancer Letter

Inside information on cancer research and drug development

Omicron: Is the light at the end of the tunnel (a) pandemic salvation, or (b) an oncoming freight train?

In Brief

MSK launches $100M Fiona and Stanley Druckenmiller Presidential Innovation Fund
Rémy Evard named chief digital officer and head of technology at MSK
Elsa Flores named associate center director of basic science at Moffitt
Alexander Stegh named Brain Tumor Center research director at Siteman
Emory Healthcare, AccessHope collaborate to extend access to cancer expertise
Robert Califf’s confirmation as FDA commissioner clears Senate HELP Committee

Drugs & Targets

FDA grants fast track designation for enobosarm in AR+ ER+ HER2- metastatic breast cancer
Carisma, Moderna to develop CAR-M therapies for cancer in $45M deal
Cullinan Oncology, Mount Sinai partner to advance novel small molecule immune modulators
FDA clears IND for P-MUC1C-ALLO1, a fully allogeneic CAR T targeting multiple solid tumors
FDA grants Breakthrough Therapy designation for CLN-081 in locally advanced or metastatic EGFR-mutated NSCLC
FDA grants Fast Track designation for Reqorsa with Keytruda in NSCLC

In The Clinic

Trials & Tribulations

Approval of an immunotherapy for adjuvant NSCLC indication gives us new reasons for finding early-stage disease

Approval of an immunotherapy for adjuvant NSCLC indication gives us new reasons for finding early-stage disease
No longer “experimental”—Prostate cancer patients should have access to proton therapy
FreeTrials & Tribulations
Removing barriers to cancer care in underserved communities
Trials & Tribulations
A FLASH flood of research relating to ultra-high dose rate radiation therapy
Trials & Tribulations
Converting Cox hazard ratios with Cox-TEL to improve interpretation of drug efficacy in checkpoint inhibitor trials
Trials & Tribulations

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The Cancer Letter is an independent weekly news publication and the leading source for information on the issues that shape oncology.

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