Sharpless reflects on his time at FDA: “The engine producing new cancer therapies and diagnostics is doing very well”

NCI Director Letai wants you to know: Grant money is flowing again post-government shutdown

The Cancer Letter’s most recent cover story featured an in-depth Q&A with Anthony G Letai, director of the National Cancer Institute.

April 15, 2026

Conversation with The Cancer Letter

Letai: Perceptions aside, money is flowing and the cancer research infrastructure is sturdy
NCI expects record-breaking spending on extramural research

Over the course of his first six months as NCI director, Anthony Letai has contended with federal budget turbulence, a record-setting government shutdown, and concerns about the flow of over research dollars.

April 10, 2026

Vol.52 No.14

By Claire Marie Porter and Paul Goldberg

Guest Editorial

America needs a new blueprint for the National Cancer Program
First step: Develop Version 2.0 of Paul Calabresi’s “Cancer at a Crossroads”

Recently, a friend lent me a copy of a decades-old report, and by old, I mean a classic.

April 10, 2026

Vol.52 No.14

By Robert A. Winn

California state-funded institute scraps selection process that put cancer projects at a disadvantage
Cancer researchers are resubmitting applications to the California Institute for Regenerative Medicine

The California Institute for Regenerative Medicine, a state agency tasked with awarding billions of dollars of scientific funding for stem cell and gene therapy, has rescinded a controversial policy that was disrupting the flow of funding to cancer research.

April 10, 2026

Vol.52 No.14

By Sara Willa Ernst

Clinical Trials & Tribulations

Protecting the cure: Why the future of radiation oncology must be precision-guided

Radiation therapy has been a cornerstone of cancer care since 1896. For more than a century, the central challenge has remained unchanged: How to eradicate tumors while preserving the normal tissues that allow patients not only to survive, but to thrive after treatment.

President’s budget request would cap indirect costs and fully fund all NIH research projects upfront

NCI has emerged relatively unscathed in the president’s FY 2027 budget request that would slash $15.8 billion from HHS funding, cut NIH overall by about 10%, eliminate three NIH institutes and centers, and move the Institute for Environmental Health Sciences and its circa $1 billion budget out of NIH.

April 10, 2026

Vol.52 No.14

By Claire Marie Porter and Jacquelyn Cobb

Sharpless reflects on his time at FDA: “The engine producing new cancer therapies and diagnostics is doing very well”

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NCI Director Letai wants you to know: Grant money is flowing again post-government shutdown

Letai: Perceptions aside, money is flowing and the cancer research infrastructure is sturdy
NCI expects record-breaking spending on extramural research

America needs a new blueprint for the National Cancer Program
First step: Develop Version 2.0 of Paul Calabresi’s “Cancer at a Crossroads”

California state-funded institute scraps selection process that put cancer projects at a disadvantage
Cancer researchers are resubmitting applications to the California Institute for Regenerative Medicine

Protecting the cure: Why the future of radiation oncology must be precision-guided

President’s budget request would cap indirect costs and fully fund all NIH research projects upfront

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Sharpless reflects on his time at FDA: “The engine producing new cancer therapies and diagnostics is doing very well”

YOU MAY BE INTERESTED IN

NCI Director Letai wants you to know: Grant money is flowing again post-government shutdown

Letai: Perceptions aside, money is flowing and the cancer research infrastructure is sturdyNCI expects record-breaking spending on extramural research

America needs a new blueprint for the National Cancer ProgramFirst step: Develop Version 2.0 of Paul Calabresi’s “Cancer at a Crossroads”

California state-funded institute scraps selection process that put cancer projects at a disadvantageCancer researchers are resubmitting applications to the California Institute for Regenerative Medicine

Protecting the cure: Why the future of radiation oncology must be precision-guided

President’s budget request would cap indirect costs and fully fund all NIH research projects upfront

Never miss an issue!

Login

Letai: Perceptions aside, money is flowing and the cancer research infrastructure is sturdy
NCI expects record-breaking spending on extramural research

America needs a new blueprint for the National Cancer Program
First step: Develop Version 2.0 of Paul Calabresi’s “Cancer at a Crossroads”

California state-funded institute scraps selection process that put cancer projects at a disadvantage
Cancer researchers are resubmitting applications to the California Institute for Regenerative Medicine