NCI Trials for August 2021

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The National Cancer Institute approved the following clinical research studies last month.  

For further information, contact the principal investigator listed.


Phase I – 10363
A Phase I Study of Pomalidomide and Nivolumab in Patients with Virus-Associated Malignancies with or Without HIV

NCI Center for Cancer Research
Lurain, Kathryn
(301) 250-5156


Phase I/II – 10417
Clinical Evaluation of ASTX727 in Combination with Venetoclax All-Oral Therapy vs Standard of Care Cytarabine and Anthracycline Induction Chemotherapy for Younger FLT3WT Patients with ELN High- Risk Acute Myeloid Leukemia

Yale University Cancer Center LAO
Savona, Michael Robert
(615) 936-3321


Phase I/II – 10428
A Phase I/II Study of Abemaciclib in Patients with HIV-Associated and HIV-Negative Kaposi Sarcoma

NCI Center for Cancer Research
Ramaswami, Ramya
(301) 451-9018


Phase II – NRG-BN010
A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on the Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma

NRG Oncology
Bagley, Stephen Joseph
(215) 614-1858


Phase III – URCC-19178
Optimizing Functional Outcomes of Older Cancer Survivors After Chemotherapy

University of Rochester NCORP Research Base
Mohile, Supriya Gupta
(585) 275-9319


Phase Pilot – AMC-111
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living with HIV: A Feasibility Study

AIDS Malignancy Consortium
Sigel, Keith Magnus
(212) 824-7558

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The U.S. House of Representatives Jan. 22 passed a three-bill minibus package that is expected to be the grand finale of the drama of the fiscal year 2026 appropriations process. The package, which funds the HHS as well as the departments of Defense, Transportation, Housing and Urban Development, Labor, and Education, gives NIH and NCI modest raises over FY25, and nullifies several  aggressive cuts the White House had proposed for NIH.

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