Leal Health establishes proprietary platform for oncologists to obtain personalized clinical trial matches for patients

Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on print

Leal, formerly known as Trialjectory, has established a proprietary platform for oncologists to quickly identify personalized clinical trial matches for their patients, reducing reliance on unstructured data and expediting patient treatment identification / clinical trial enrollment. The platform is free for oncologists. 

Leal is an AI-powered decision support platform that aims to democratize patient access to advanced cancer treatments. Its goal is to allow the pharmaceutical and biotech industry to execute patient-centric clinical trials

Leveraging AI, Leal’s technology identifies relevant and available clinical trial options for oncologists to present to their patients. It also allows oncologists to customize clinical trial searches through specifying cancer subtypes, biomarkers. and other criteria.

“Traditionally, oncologists have relied on either the major academic centers in the U.S. or on ClinicalTrials.gov to identify potential studies for cancer patient enrollment,” Leonard Lichtenfeld, Leal advisor and former Chief Medical and Scientific Officer at the American Cancer Society, said in a statement. “The problem is that these large research hospitals, while highly reputable, do not always have clinical trials that work best for a patient’s unique medical and personal needs. Furthermore, community oncologists, who play a crucial role in providing care in communities where specialized cancer centers are less accessible, often do not have relationships with the major centers.”

Leal is the largest AI pre-screening platform for clinical trials. Leal says it has facilitated more than 4 million treatment matches, with approximately 20,000 clinical trials and 150,000 cancer patients on its platform. Leal supports over 22 cancer types, covering 95 percent of cancers.

Table of Contents

YOU MAY BE INTERESTED IN

The NHS-Galleri trial presented at ASCO was the largest, prospective, randomized trial of a multicancer early detection test (MCED) to date. The study enrolled approximately 143,000 asymptomatic adults (ages 50-77) and was the first of its kind to assess clinical utility of an MCED test for cancer screening. 
The ASCERTAIN-V phase I/II clinical trial, which evaluated the first all-oral regimen of decitabine-cedazuridine plus venetoclax in patients with newly diagnosed acute myeloid leukemia who are ineligible for intensive induction chemotherapy, demonstrated favorable response rates and survival with expected myelosuppressive effects.
Talvey (talquetamab-tgvs), a GPRC5D bispecific antibody, in combination with Darzalez Faspro (daratumumab and hyaluronidase-fihj) with or without pomalidomide demonstrated significant reduction in the risk of disease progression or death of up to 72% and clinically meaningful reduction of up to 53% in the risk of death compared to the standard regimen of Darzalez Faspro, pomalidomide, and dexamethasone in patients with relapsed/refractory multiple myeloma, according to the results of the investigational phase III MonumenTAL-3 study. 
Jaypirca (pirtobrutinib), a non-covalent Bruton tyrosine kinase inhibitor, plus a two-year venetoclax and rituximab regimen versus venetoclax and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma reduced the risk of disease progression or death by 45% (HR=0.55 [95% CI, 0.40-0.75]; p=0.0001), according to the results of the phase III BRUIN CLL-322 trial. The study met its primary endpoint of independent review committee-assessed progression-free survival.

Never miss an issue!

Get alerts for our award-winning coverage in your inbox.

Login