The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Keytruda + Lenvima demonstrates long-term, durable survival benefit vs. sunitinib as first-line treatment for advanced RCC in phase III trial

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After four years of follow-up, final pre-specified overall survival analysis from the pivotal phase III CLEAR/KEYNOTE-581 trial showed that Keytruda plus Lenvima maintained a clinically meaningful OS benefit versus sunitinib for the first-line treatment of patients with advanced renal cell carcinoma, reducing the risk of death by 21%. 

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