Merck joins ORIEN

Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on print

M2Gen said Merck has joined the Oncology Research Information Exchange Network (ORIEN) Avatar Research Program.

Launched in April 2016, the ORIEN Avatar Research Program fosters collaboration among key stakeholders in cancer research, including patients themselves, with the shared goal of discovering and developing novel therapies and ultimately matching patients to the best treatment options.

ORIEN Avatar is a collaboration between leading U.S. cancer hospitals, pharmaceutical companies and M2Gen, which manages the program. Patients donate clinical and molecular data through their consent to the Total Cancer Care Protocol; that data is then utilized by the ORIEN cancer center members and pharmaceutical partners to speed discoveries and match eligible patients to cutting-edge trials.

The program represents an unprecedented, pre-competitive approach to fighting cancer, designed to accelerate the discovery and development of novel therapies for millions of patients. Merck’s participation in the program builds on a history of collaboration dating back to the founding of M2Gen in 2006, to operationalize a multi-year agreement based on the Total Cancer Care Protocol.

The ORIEN Avatar Research Program links pharmaceutical companies and prominent cancer centers.

Participating cancer researchers contribute samples and disease information from patients who provide consent to be studied via the Total Cancer Care Protocol, and receive rich molecular data plus access to a rich network of potential collaborators.

Pharmaceutical companies contribute financial support and receive access to de-identified genetic and disease information that can be used to inform the discovery and clinical development of novel cancer therapeutics.

Table of Contents

YOU MAY BE INTERESTED IN

Secretary of the U.S. Department of Health and Human Services Robert F. Kennedy Jr. appeared before the House Energy and Commerce Subcommittee on Health to defend the HHS fiscal year 2026 budget proposal, and faced criticism from several Democratic lawmakers on what they described as a lack of transparency and scientific rigor in the agency’s recent decisions.

The full-scale Russian invasion of Ukraine has devastated the Ukrainian healthcare infrastructure, disrupting cancer care, halting clinical trials, and compounding long-standing systemic challenges.  Even before the war, Ukraine’s oncology system faced major constraints: Limited access to radiotherapy equipment, outdated chemotherapy supply chains, and workforce shortages. The invasion intensified these issues—cancer hospitals were damaged, warehouses destroyed,...

Patients affected by cancer are increasingly turning to artificial intelligence-powered chatbots, such as ChatGPT and Gemini, for answers to pressing health questions. These tools, available around the clock and free from geographic or scheduling constraints, are appealing when access to medical professionals is limited by financial, language, logistical, or emotional barriers. 

Never miss an issue!

Get alerts for our award-winning coverage in your inbox.

Login