FDA granted Orphan Drug Designation to TK216 for the treatment of Ewing sarcoma. Oncternal Therapeutics Inc., the drug’s sponsor, is in the process of initiating a first-in-human phase I trial of TK216 in relapsed or refractory Ewing sarcoma. The company recently received Fast Track Designation in this indication. TK216 is a first-in-class small molecule that...
Leadership is changing at The Wistar Institute and the Helen F. Graham Cancer Center & Research Institute in the months to come—but the leaders of the two institutions say that this will have little if any effect on the clinical-research collaboration that they have spent the past 15years building (The Cancer Letter, July 12, 2019).
