The Cancer Letter

The leading source for information on the issues that shape oncology since 1973

Drugs & Targets

ADXS-HPV grated orphan drug designation

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FDA granted orphan drug designation to ADXS-HPV for the treatment of stage II-IV invasive cervical cancer. ADXS-HPV is an immunotherapy drug candidate, developed by Advaxis Inc., which is designed to target cells expressing the HPV gene E7. Expression of the E7 gene from high-risk HPV variants is responsible for the transformation of infected cells into...

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