An analysis comparing sentinel lymph node biopsy procedures using Lymphoseek (technetium Tc 99m tilmanocept) injection and vital blue dye to filtered sulfur colloid and VBD in breast cancer patients showed that Lymphoseek patients had significantly fewer sentinel lymph nodes removed per procedure (mean: 1.85 vs. 3.24; p < 0.0001).
In 1999, Richard Pazdur, a GI oncologist at MD Anderson, saw an FDA recruitment ad in The New England Journal of Medicine. The agency was looking for a director of the FDA Division of Oncology Drug Products.
