An analysis comparing sentinel lymph node biopsy procedures using Lymphoseek (technetium Tc 99m tilmanocept) injection and vital blue dye to filtered sulfur colloid and VBD in breast cancer patients showed that Lymphoseek patients had significantly fewer sentinel lymph nodes removed per procedure (mean: 1.85 vs. 3.24; p < 0.0001).
In a unanimous vote, the FDA Oncologic Drugs Advisory Committee advised the agency to accept the metric of “minimal residual disease,” or MRD, as a basis for accelerated approvals of therapies in all settings of multiple myeloma.
