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USC study offers insights on leukemia progression and chemotherapy resistance

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A team of scientists led by Rong Lu from USC and Akil A. Merchant from Cedars-Sinai introduced a genetic technology correlating gene expression signatures with cancer progression and chemotherapy resistance in leukemia. 

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Howard Hughes Medical Institute Investigator David R. Liu was awarded the 2025 Breakthrough Prize in Life Sciences for developing two gene-editing technologies—known as base editing and prime editing—which enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases. 
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