USC comparison study of leading targeted therapies for ALK+ lung cancer could lead to better treatment decisions

American Lung Association announces grant winners of $21M in funding for lung health research

The American Lung Association Research Institute announced it invested $21 million in research and related scientific activities.

November 06, 2026

Vol.52 No.41

Clinical Roundup

Tarlatamab + durvalumab extends survival for patients with aggressive small cell lung cancer, phase III trial finds

In patients with extensive-stage small cell lung cancer, tarlatamab, a bispecific T-cell engager, plus durvalumab as first-line maintenance therapy extended median overall survival by more than eight months, more than tripled progression-free survival, and reduced the risk of death by 58% compared to durvalumab alone, according to the results of the phase III open-label, multicenter, randomized DeLLphi-305 study.

November 06, 2026

Vol.52 No.41

Clinical Roundup

Divarasib monotherapy improves OS in previously-treated KRAS G12C-mutated lung cancer, phase III trial finds

Divarasib, a next-generation KRAS G12C inhibitor, lowered the risk of disease progression or death by 42% and the overall risk of death by 44% in people with previously treated KRAS G12C-mutated non-small cell lung cancer, according to the results from the phase III Krascendo 1 study. The therapy demonstrated the superior efficacy compared with current standard of care KRAS G12C inhibitors.

October 30, 2026

Vol.52 No.40

Podcast

As USPSTF falters, the idea that “screening is always good” is gaining traction

With the pope’s lung cancer diagnosis jumpstarting conversations about lung cancer screening and the constant buzz surrounding multi-cancer detection tests, evidence-based evaluation of screening tests is more important than ever.

October 21, 2026

News Analysis

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Pope Leo XIV has been diagnosed with lung adenocarcinoma. According to missives from the Holy See, the pope underwent surgery to remove the lower lobe of his right lung Oct. 13.

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

Chronic exposure to cigarette smoke may reprogram different populations of lung stem cells, which maintain and repair lung tissue, in ways that make them vulnerable to specific cancer-causing gene alterations and ultimately helps determine the type of lung cancer that develops.

October 09, 2026

Vol.52 No.37

USC comparison study of leading targeted therapies for ALK+ lung cancer could lead to better treatment decisions

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American Lung Association announces grant winners of $21M in funding for lung health research

Tarlatamab + durvalumab extends survival for patients with aggressive small cell lung cancer, phase III trial finds

Divarasib monotherapy improves OS in previously-treated KRAS G12C-mutated lung cancer, phase III trial finds

As USPSTF falters, the idea that “screening is always good” is gaining traction

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

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USC comparison study of leading targeted therapies for ALK+ lung cancer could lead to better treatment decisions

YOU MAY BE INTERESTED IN

American Lung Association announces grant winners of $21M in funding for lung health research

Tarlatamab + durvalumab extends survival for patients with aggressive small cell lung cancer, phase III trial finds

Divarasib monotherapy improves OS in previously-treated KRAS G12C-mutated lung cancer, phase III trial finds

As USPSTF falters, the idea that “screening is always good” is gaining traction

The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”

Cigarette smoke may prime lung stem cells for different types of lung cancer, Hopkins study finds

Never miss an issue!

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The lung cancer diagnosis of Pope Leo—believed to be a never-smoker—sparks conversations around screening
“Even when the patient is the pope, advances in cancer treatment don’t arrive by divine intervention.”