UTSW researchers identify central signaling pathway that enables survival without the need for genetic change

New framework developed for treating liver cancer by UT Southwestern-led research could lead to updated standards

A multidisciplinary team co-led by Amit Singal, chief of hepatology and director of the Liver Tumor Program in the Division of Digestive and Liver Diseases at UT Southwestern Medical Center, has developed new treatment recommendations for liver cancer that incorporate the latest research and an expanding range of therapeutic options.

September 11, 2026

Vol.52 No.33

Clinical Roundup

UTSW study shows how RNA-modifying enzyme linked to cancer picks its targets

An RNA-modifying enzyme linked to cancer and neurological disorders selects its targets by recognizing specific RNA shapes and sequences, according to a study by UT Southwestern Medical Center researchers.

July 02, 2026

Vol.52 No.26

Clinical Roundup

Antibody may improve treatment response in lung cancer, UTSW-led study finds

An experimental antibody treatment that binds to a protein known as PCDH7 shrank tumors in preclinical models of non-small cell lung cancer, even those resistant to a targeted therapy, a study led by UT Southwestern Medical Center researchers showed. This discovery could eventually lead to a new class of drugs to treat NSCLC and potentially other cancers.

June 18, 2026

Vol.52 No.24

Clinical Roundup

Ovarian cancer cells use stress hormone signaling to shut down immune system, UTSW study finds

When activated in ovarian cancer cells, the receptor for the body’s primary stress hormone alters the tumor environment in ways that blunt immune response, according to research led by UT Southwestern Medical Center.

May 29, 2026

Vol.52 No.21

Clinical Roundup

DNA sequencing tool reveals hidden mutations that can drive cancer

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.

October 10, 2025

Vol.51 No.37

Cancer Policy

Trump releases executive order that demands “Restoring Gold Standard Science”

President Trump has issued an executive order, titled “Restoring Gold Standard Science,” which “ensures that agencies practice data transparency, acknowledge relevant scientific uncertainties, are transparent about the assumptions and likelihood of scenarios used, approach scientific findings objectively, and communicate scientific data accurately.”

May 30, 2025

Vol.51 No.21

By Jacquelyn Cobb

UTSW researchers identify central signaling pathway that enables survival without the need for genetic change

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New framework developed for treating liver cancer by UT Southwestern-led research could lead to updated standards

UTSW study shows how RNA-modifying enzyme linked to cancer picks its targets

Antibody may improve treatment response in lung cancer, UTSW-led study finds

Ovarian cancer cells use stress hormone signaling to shut down immune system, UTSW study finds

DNA sequencing tool reveals hidden mutations that can drive cancer

Trump releases executive order that demands “Restoring Gold Standard Science”

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