MD Anderson researchers, led by Renata Ferrarotto, conducted a phase II trial evaluating the combination of the VEGFR inhibitor axitinib plus the PD-L1 inhibitor avelumab in 28 patients with progressive recurrent or metastatic adenoid cystic carcinoma, a rare salivary gland cancer for which there are limited treatment options.
Homologous recombination deficiency tests are used routinely in the clinic to determine which patients get PARP inhibitors.
