Amid funding cuts and firings, cancer groups seek relief from judges, in Congress—and in the court of public opinion

Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care

For a year before an osteosarcoma was found in her right proximal tibia, Sammy Ulloa, pushing through pain, persisted with her training as a Division I track and field and cross-country competitor.

April 11, 2025

Vol.51 No.14

By Claire Marie Porter

Amid HHS upheaval, Bhattacharya takes the helm at NIH, Makary at FDA
Meanwhile, NASEM sounds “SOS” for health infrastructure

The day before health economist Jay Bhattacharya stepped into his new role as NIH director, he sent a document to his employees outlining his top five priorities for the department, which included “reproducibility” and “transparency,” two themes he discussed at his confirmation hearings (The Cancer Letter, March 7, 2025).

April 04, 2025

Vol.51 No.13

By Claire Marie Porter, Paul Goldberg and Jacquelyn Cobb

Clinical Roundup

Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers

Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated PDAC development in mice, according to results of a study published in Cancer Research, a journal of the American Association for Cancer Research.

April 04, 2025

Vol.51 No.13

Clinical Roundup

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer, Baylor Medicine study finds

A study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer to develop resistance to therapy. Researchers at Baylor College of Medicine showed that lipid accumulation in tumor cells and nearby immune cells promotes immune suppression, but disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment.

April 04, 2025

Vol.51 No.13

Podcast

In The Headlines: HHS shakeup threatens a legacy of medical breakthroughs

“For the last 50 years every major medical breakthrough can be traced back to investments in the NIH, which houses the National Cancer Institute (NCI),” said Wayne A. I. Frederick, interim chief executive officer of American Cancer Society and the American Cancer Society Cancer Action Network.

April 02, 2025

Vol.51 No.12

In Brief

Keith Flaherty to become president-elect of AACR for 2025-2026, Michael Caligiuri named treasurer

The members of the American Association for Cancer Research have elected Keith T. Flaherty, fellow of the AACR Academy, as the AACR president-elect for 2025-2026.

March 28, 2025

Vol.51 No.12

Amid funding cuts and firings, cancer groups seek relief from judges, in Congress—and in the court of public opinion

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Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care

Amid HHS upheaval, Bhattacharya takes the helm at NIH, Makary at FDA
Meanwhile, NASEM sounds “SOS” for health infrastructure

Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer, Baylor Medicine study finds

In The Headlines: HHS shakeup threatens a legacy of medical breakthroughs

Keith Flaherty to become president-elect of AACR for 2025-2026, Michael Caligiuri named treasurer

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Amid funding cuts and firings, cancer groups seek relief from judges, in Congress—and in the court of public opinion

YOU MAY BE INTERESTED IN

Only half of adolescents and young adults with cancer get fertility counseling before treatmentOncofertility consult is an oft-overlooked standard of care

Amid HHS upheaval, Bhattacharya takes the helm at NIH, Makary at FDAMeanwhile, NASEM sounds “SOS” for health infrastructure

Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers

Fatty acids promote immune suppression and therapy resistance in triple negative breast cancer, Baylor Medicine study finds

In The Headlines: HHS shakeup threatens a legacy of medical breakthroughs

Keith Flaherty to become president-elect of AACR for 2025-2026, Michael Caligiuri named treasurer

Never miss an issue!

Login

Only half of adolescents and young adults with cancer get fertility counseling before treatment
Oncofertility consult is an oft-overlooked standard of care

Amid HHS upheaval, Bhattacharya takes the helm at NIH, Makary at FDA
Meanwhile, NASEM sounds “SOS” for health infrastructure