The National Cancer Institute approved the following clinical research studies last month.
For further information, contact the principal investigator listed.
Phase I – 10433
Phase I/Ib Trial Evaluating the Safety and Efficacy of BET Inhibitor, ZEN003694 with PD-1 Inhibitor, Nivolumab with or Without CTLA-4 Inhibitor, Ipilimumab in Solid Tumors
UPMC Hillman Cancer Center LAO
Mahdi, Haider Salih
(216) 445-7069
Phase I – 10440
A Phase 1/1a Study of Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for Relapsed/Refractory Light Chain Amyloidosis
City of Hope Comprehensive Cancer Center LAO
Rosenzweig, Michael A.
(626) 256-4673
Phase I – PBTC-059
Phase 1 Trial of Autologous HER2-Specific CAR T Cells in Pediatric Patients with Refractory or Recurrent Ependymoma
Pediatric Brain Tumor Consortium
Hegde, Meenakshi
(832) 824-4840
Phase II – 10466
A Phase 2 Study of Bevacizumab, Erlotinib and Atezolizumab in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Associated or Sporadic Papillary Renal Cell Cancer
National Cancer Institute LAO
Srinivasan, Ramaprasad
(240) 760-6251
Phase II – 10476
A Randomized Phase 2 Study of Combination Atezolizumab and CDX-1127 (Varlilumab) with or Without Addition of Cobimetinib in Previously Treated Unresectable Biliary Tract Cancers
JHU Sidney Kimmel Comprehensive Cancer Center LAO
Azad, Nilofer Saba
(410) 614-9169
Phase II – A021901
Randomized Phase II Trial of Lutetium Lu 177 Dotatate Versus Everolimus in Somatostatin Receptor Positive Bronchial Neuroendocrine Tumors
Alliance for Clinical Trials in Oncology
Hope, Thomas A.
(415) 353-7065
Phase II – A09200
Phase 2 Randomized Trial of Neoadjuvant or Palliative Chemotherapy with or Without Immunotherapy for Peritoneal Mesothelioma
Alliance for Clinical Trials in Oncology
Mansfield, Aaron S.
(507) 293-0569
Phase II – S1934
NASSIST (Neoadjuvant Chemoradiation +/- Immunotherapy Before Surgery for Superior Sulcus Tumors): A Randomized Phase II Trial of Trimodality +/- Atezolizumab in Resectable Superior Sulcus Non-Small Cell Lung Cancer
SWOG
Osarogiagbon, Raymond Uyiosa
(901) 355-6340
