Amgen and Immatics collaborate to develop cancer immunotherapies

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Amgen and Immatics Biotechnologies GmbH announced a research collaboration and exclusive license agreement to develop next-generation, T-cell engaging bispecific immunotherapies targeting multiple cancers.

The collaboration will combine Immatics’ XPRESIDENT target discovery and T-cell receptor capabilities with Amgen’s validated Bispecific T-cell Engager technology, with the aim of creating novel oncology drugs. Amgen will be responsible for clinical development, manufacturing, and commercialization worldwide.

Under the agreement, Immatics will receive an upfront fee of $30 million and is eligible to receive over $500 million in development, regulatory and commercial milestone payments for each program and tiered royalties up to a double-digit percentage of net sales.

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