Patients with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma that received Imbruvica (ibrutinib) in combination with bendamustine and rituximab experienced an 80 percent reduction in the risk of progression or death when compared to patients receiving bendamustine, rituximab and placebo in a phase III trial.
In two back-to-back, all-day meetings, the FDA Oncologic Drugs Advisory Committee considered four thorny applications that the agency appeared to have been saving up as a result of the pause in activity that followed President Trump’s return to office.
