Phase II Imbruvica Trial Shows 47% of MCL Patients Alive at 27-Month Median Follow-up

With early-onset colorectal cancer on the rise, CRC screening is no longer just your parents’ problem

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April 01, 2026

The Directors: Wistar’s Altieri and ChristianaCare’s Petrelli say partnership of their institutions will go on as the guard changes

Leadership is changing at The Wistar Institute and the Helen F. Graham Cancer Center & Research Institute in the months to come—but the leaders of the two institutions say that this will have little if any effect on the clinical-research collaboration that they have spent the past 15years building (The Cancer Letter, July 12, 2019).

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Vol.52 No.12

By Sara Willa Ernst and Paul Goldberg

Clinical Trials & Tribulations

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

The incidence of multiple cancer types in people under the age of 50 has been rising, with early-onset cancers now contributing to nearly 15,000 excess cases of cancer in the U.S. annually.

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Vol.52 No.12

By W. Kimryn Rathmell

Trials & Tribulations

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

March is National Colorectal Cancer Awareness Month. It is a reminder of a heartbreaking trend that oncologists like me are witnessing in our clinics: Last year, for the first time, colorectal cancer became the leading cause of cancer-related death in Americans under the age of 50, according to data published earlier this year in JAMA.

March 27, 2026

Vol.52 No.12

By Richard M. Goldberg

Clinical

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?

Three decades ago, colorectal cancer was the fifth leading cause of cancer death in patients under 50 years old. For a physician treating the average 45-year-old, colorectal cancer was not a diagnosis that immediately came to mind.

Michael Bishop, Nobel-winning cancer researcher, dies at 90

UC San Francisco Chancellor emeritus J. Michael Bishop, a pioneering microbiologist who shared the 1989 Nobel Prize in Physiology or Medicine for discovering that every cell in the body harbors genes that can cause cancer, died March 20. He was 90.

March 27, 2026

Vol.52 No.12

By UCSF Communications Staff

Phase II Imbruvica Trial Shows 47% of MCL Patients Alive at 27-Month Median Follow-up

YOU MAY BE INTERESTED IN

With early-onset colorectal cancer on the rise, CRC screening is no longer just your parents’ problem

The Directors: Wistar’s Altieri and ChristianaCare’s Petrelli say partnership of their institutions will go on as the guard changes

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?

Michael Bishop, Nobel-winning cancer researcher, dies at 90

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Phase II Imbruvica Trial Shows 47% of MCL Patients Alive at 27-Month Median Follow-up

YOU MAY BE INTERESTED IN

With early-onset colorectal cancer on the rise, CRC screening is no longer just your parents’ problem

The Directors: Wistar’s Altieri and ChristianaCare’s Petrelli say partnership of their institutions will go on as the guard changes

Early-onset cancer is on the rise. Here is how OSUCCC–James is adapting to the needs of younger patients

In the era of immunotherapy, response rate alone fails to predict true patient benefitRegulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50Why aren’t 45-year-olds getting their recommended CRC screenings?

Michael Bishop, Nobel-winning cancer researcher, dies at 90

Never miss an issue!

Login

In the era of immunotherapy, response rate alone fails to predict true patient benefit
Regulators must adapt

Colorectal cancer is now the leading cause of cancer death in patients under 50
Why aren’t 45-year-olds getting their recommended CRC screenings?