Canine osteosarcoma data highlights growing role of comparative oncology

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OST-HER2, together with palliative radiation therapy, increased median overall survival time in treated dogs from 159 days vs. 124 days in the RT-alone control group (p = 0.0237), according to the results of phase II clinical canine trial. The treatment was aimed at preventing amputation in frontline canine osteosarcoma.

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Researchers from the Broad Institute of MIT and Harvard, the University of Georgia, and the One Health Company have published the results from the largest-ever genomic sequencing study of canine tumors. The study shows that dog and human cancers are far more genetically similar than previously known and underscores the important role of canine cancer data in accelerating the development of precision treatments for cancer patients of both species.

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