UTSW study shows how RNA-modifying enzyme linked to cancer picks its targets

New framework developed for treating liver cancer by UT Southwestern-led research could lead to updated standards

A multidisciplinary team co-led by Amit Singal, chief of hepatology and director of the Liver Tumor Program in the Division of Digestive and Liver Diseases at UT Southwestern Medical Center, has developed new treatment recommendations for liver cancer that incorporate the latest research and an expanding range of therapeutic options.

September 11, 2026

Vol.52 No.33

Clinical Roundup

Antibody may improve treatment response in lung cancer, UTSW-led study finds

An experimental antibody treatment that binds to a protein known as PCDH7 shrank tumors in preclinical models of non-small cell lung cancer, even those resistant to a targeted therapy, a study led by UT Southwestern Medical Center researchers showed. This discovery could eventually lead to a new class of drugs to treat NSCLC and potentially other cancers.

June 18, 2026

Vol.52 No.24

Clinical Roundup

Ovarian cancer cells use stress hormone signaling to shut down immune system, UTSW study finds

When activated in ovarian cancer cells, the receptor for the body’s primary stress hormone alters the tumor environment in ways that blunt immune response, according to research led by UT Southwestern Medical Center.

May 29, 2026

Vol.52 No.21

Clinical Roundup

UTSW researchers identify central signaling pathway that enables survival without the need for genetic change

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes—an ability known as phenotypic plasticity.

May 22, 2026

Vol.52 No.20

UTSW study shows how RNA-modifying enzyme linked to cancer picks its targets

YOU MAY BE INTERESTED IN

New framework developed for treating liver cancer by UT Southwestern-led research could lead to updated standards

Antibody may improve treatment response in lung cancer, UTSW-led study finds

Ovarian cancer cells use stress hormone signaling to shut down immune system, UTSW study finds

UTSW researchers identify central signaling pathway that enables survival without the need for genetic change

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