Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.
Spatial mapping experiments reveal that topologically associating domains in individual cells tend to take a globular shape, according to a study conducted by scientists at Sanford Burnham Prebys and colleagues in Hong Kong.
