Breast cancer mortality continues three-decade decline, but steeper increases for women under 50 & AAPI women of all ages

Eric Small, ASCO’s immediate past president, speaks on the toll of toxicity—financial, emotional, physical—in cancer
“Discovery alone is not enough. It’s about what becomes of what we discover. It’s about translation.”

In a poignant keynote punctuated with anecdotes about grief, American Society of Clinical Oncology’s immediate past president Eric Small emphasized that the annual conference is not just about scientific discovery, but about a responsibility to translate discoveries into better outcomes for cancer patients globally.

June 05, 2026

Vol.52 No.22

By Claire Marie Porter

Clinical Roundup

Camizestrant combination delayed time to first progression by 55% in patients with advanced HR+ breast cancer with ESR1 tumor mutation

Further positive results from the phase III SERENA-6 trial showed camizestrant plus a cyclin-dependent kinase 4/6 inhibitor—palbociclib, ribociclib or abemaciclib—maintained its progression-free survival benefit with longer follow-up and delivered a statistically significant and clinically meaningful improvement in second progression-free survival, demonstrating sustained benefit beyond initial treatment.

June 05, 2026

Vol.52 No.22

Clinical Trials & Tribulations

As rural cancer disparities persist, aligning policy with care delivery models can close the gap

Across the United States, rural communities bear a disproportionate and growing burden of cancer mortality.

May 29, 2026

Vol.52 No.21

By Matthew L. Anderson

Drugs & Targets

FDA approves Enhertu in HER2+ early breast cancer for both neoadjuvant and adjuvant treatment

FDA approved Enhertu (fam-trastuzumab deruxtecan-nxki) for both the neoadjuvant and adjuvant treatment of patients with HER2-positive early breast cancer based on results from the DESTINY-Breast11 and DESTINY-Breast05 Phase III trials, respectively.

May 22, 2026

Vol.52 No.20

Cancer History Project Podcast

“Backwater to Blockbuster” chronicles the previously untold story of the explosive growth of St. Jude Children’s Research Hospital
In a conversation with Deborah Doroshow, co-authors Chuck Sherr and Bill Evans discuss their collaborative writing process

“Backwater to Blockbuster,” the first de novo book published by the Cancer History Project, traces the evolution of St. Jude Children’s Research Hospital to its current status of a powerhouse of research in pediatric cancer.

May 15, 2026

Vol.52 No.19

By Claire Marie Porter

In Brief

LSU LCMC Health cancer center strengthens cancer clinical trials infrastructure to expand access across Louisiana

The LSU LCMC Health Cancer Center expanded its Cancer Clinical Trials Office.

May 15, 2026

Vol.52 No.19

Breast cancer mortality continues three-decade decline, but steeper increases for women under 50 & AAPI women of all ages

YOU MAY BE INTERESTED IN

Eric Small, ASCO’s immediate past president, speaks on the toll of toxicity—financial, emotional, physical—in cancer
“Discovery alone is not enough. It’s about what becomes of what we discover. It’s about translation.”

Camizestrant combination delayed time to first progression by 55% in patients with advanced HR+ breast cancer with ESR1 tumor mutation

As rural cancer disparities persist, aligning policy with care delivery models can close the gap

FDA approves Enhertu in HER2+ early breast cancer for both neoadjuvant and adjuvant treatment

“Backwater to Blockbuster” chronicles the previously untold story of the explosive growth of St. Jude Children’s Research Hospital
In a conversation with Deborah Doroshow, co-authors Chuck Sherr and Bill Evans discuss their collaborative writing process

LSU LCMC Health cancer center strengthens cancer clinical trials infrastructure to expand access across Louisiana

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Breast cancer mortality continues three-decade decline, but steeper increases for women under 50 & AAPI women of all ages

YOU MAY BE INTERESTED IN

Eric Small, ASCO’s immediate past president, speaks on the toll of toxicity—financial, emotional, physical—in cancer“Discovery alone is not enough. It’s about what becomes of what we discover. It’s about translation.”

Camizestrant combination delayed time to first progression by 55% in patients with advanced HR+ breast cancer with ESR1 tumor mutation

As rural cancer disparities persist, aligning policy with care delivery models can close the gap

FDA approves Enhertu in HER2+ early breast cancer for both neoadjuvant and adjuvant treatment

“Backwater to Blockbuster” chronicles the previously untold story of the explosive growth of St. Jude Children’s Research HospitalIn a conversation with Deborah Doroshow, co-authors Chuck Sherr and Bill Evans discuss their collaborative writing process

LSU LCMC Health cancer center strengthens cancer clinical trials infrastructure to expand access across Louisiana

Never miss an issue!

Login

Breast cancer mortality continues three-decade decline, but steeper increases for women under 50 & AAPI women of all ages

Eric Small, ASCO’s immediate past president, speaks on the toll of toxicity—financial, emotional, physical—in cancer
“Discovery alone is not enough. It’s about what becomes of what we discover. It’s about translation.”

“Backwater to Blockbuster” chronicles the previously untold story of the explosive growth of St. Jude Children’s Research Hospital
In a conversation with Deborah Doroshow, co-authors Chuck Sherr and Bill Evans discuss their collaborative writing process