The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Combination targeted treatment produces lasting remissions in resistant aggressive DLBCL in phase Ib/II study

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NIH researchers have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to standard treatments. The five-drug combination targets multiple molecular pathways that diffuse large B-cell lymphoma tumors use to survive.

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