Researchers have shown for the first time exactly how immature neutrophils—white blood cells that are an important part of the immune system—are hijacked by pancreatic cancers to drive immunosuppression and treatment resistance. The study, led by investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, was published in Cancer Discovery.
Researchers have identified groups of patients with pleural mesothelioma, a rare and aggressive cancer, who are more likely to respond to immunotherapy, offering clues about why only some tumors respond to the treatment.
