COVID-19 vaccine breakthroughs in cancer patients on the rise due to omicron

Phase II study of personalized cancer vaccine in CRC shows positive preliminary PFS and long-term ctDNA data

The ongoing, signal-seeking phase II portion of the phase II/III study evaluating Granite, a personalized neoantigen cancer vaccine, in front-line metastatic microsatellite stable colorectal cancer, produced positive preliminary data.

April 05, 2024

Vol.50 No.14

In the Archives

Yale’s Richard Edelson on what got him started in research for cutaneous T-cell lymphoma

Richard Edelson began his career at NCI, where he was training to become a cancer immunologist.

October 27, 2023

Vol.49 No.40

Clinical Roundup

COVID-19 pandemic associated with decline in number of reported cancer cases

The COVID-19 pandemic was associated with significant changes in diagnoses of all cancer types in 2020, with a 14.4% overall decline in the number of reported cancer cases in cancer centers accredited by the Commission on Cancer (CoC) compared with the prior year.

October 27, 2023

Vol.49 No.40

Clinical Roundup

Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer

A study demonstrated that viral immune evasion enabled breakthrough infections of COVID-19 in patients with lung cancer, highlighting the importance of effective monitoring mechanisms, such as anti-N serology, to track infection rates in specific vulnerable populations.

October 27, 2023

Vol.49 No.40

In Brief

Katalin Karikó, Drew Weissman awarded 2023 Nobel Prize in Physiology or Medicine for mRNA vaccine research

Katalin Karikó (left) and Drew Weissman (right)Photo credit: Niklas Elmehed © Nobel Prize OutreachKatalin Karikó and Drew Weissman were jointly awarded the 2023 Nobel Prize in Physiology or Medicine “for their discoveries concerning base modifications that enabled the development of effective mRNA vaccines against COVID-19.”

October 13, 2023

Vol.49 No.38

Clinical Roundup

UPMC “weighted” lottery program improved equity in allocation of scarce medication

A “weighted” lottery program designed to ensure that people living in the most disadvantaged U.S. neighborhoods would be offered a scarce, potentially life-saving medication proved feasible in a large health system. The approach can improve equity in receipt of the drug by people disproportionately affected by disease, according to an analysis published today in JAMA Health Forum by University of Pittsburgh and UPMC scientist-clinicians.

September 08, 2023

Vol.49 No.33

COVID-19 vaccine breakthroughs in cancer patients on the rise due to omicron

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Phase II study of personalized cancer vaccine in CRC shows positive preliminary PFS and long-term ctDNA data

Yale’s Richard Edelson on what got him started in research for cutaneous T-cell lymphoma

COVID-19 pandemic associated with decline in number of reported cancer cases

Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer

Katalin Karikó, Drew Weissman awarded 2023 Nobel Prize in Physiology or Medicine for mRNA vaccine research

UPMC “weighted” lottery program improved equity in allocation of scarce medication

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