Yale, Maryland study: IXA+BEV effective for patients with advanced ovarian cancer

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A study led by researchers at Yale Cancer Center and the University of Maryland Comprehensive Cancer Center showed that ixabepilone plus bevacizumab (IXA+BEV) is a well-tolerated, effective combination for treatment of platinum/taxane-resistant ovarian cancer compared to ixabepilone (IXA) alone. The data show it also may significantly extend both progression free survival and overall survival. 

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The European Medicines Agency’s Committee for Medicinal Products for Human Use adopted a positive opinion recommending approval a Type II variation for Rubraca (rucaparib), as a first-line maintenance treatment for all women with advanced ovarian cancer regardless of their BRCA mutation status, who have responded to first-line platinum-based chemotherapy. 

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