Four out of five cancer therapies tested in phase III trials do not achieve clinically-meaningful benefit in prolonging survival

The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty
“We are resolute. We are committed to continuing to move the work forward.”

Speaking on The Cancer Letter Podcast, Taofeek Kunle Owonikoko recalled recent conversations with two junior faculty members at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center.

April 18, 2025

Vol.51 No.15

By Paul Goldberg

Trump administration seeks to slash NIH by roughly 40% as 27 institutes and centers are whittled down to eight
NCI to remain intact, but its finances are uncertain; FDA is spared big cuts

Confidential Trump administration budget documents show that the upcoming FY26 Budget Request will radically cut about $50 billion out of the U.S. Department of Health and Human Services, reshuffling agency components, and slashing the number of NIH institutes and centers to just eight.

RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”
Whistleblowers will be “honored”

As he addressed FDA employees, HHS Secretary Robert F. Kennedy Jr. described the Trump era as a “generational opportunity to make the regulatory agency live up to its foundational ideals” and emerge from the morass of what he described as the “deep state.”

TIL + pembro regimen achieves 24% response rate in solid epithelial tumors, marking a step forward in immunotherapy research

Immunotherapy has changed the course of blood cancers and melanomas, but is stubbornly ineffective for the treatment of most epithelial solid cancers—the cancers that kill about 90% of the more than 600,000 Americans who die of cancer each year.

What would Mary do?
Trump’s actions call for Lasker-style advocacy

A diagnosis of cancer brings with it fear and uncertainty. Changes proposed by the Trump administration pose a grave new risk to those who suffer from cancer today or will suffer from cancer in the future. A future which was increasingly optimistic is suddenly far more threatening.

April 18, 2025

Vol.51 No.15

By Kevin J. Cullen

City of Hope’s BMT program performs 20,000th transplant
49-year history creates 20,000 tomorrows

This year marks the 49th anniversary of the City of Hope bone marrow transplant program, which was conceived and developed by Ernest Beutler and Karl Blume in 1975, with help and inspiration from E. Donnall Thomas, the 1990 Nobel Laureate in Physiology and Medicine.

April 18, 2025

Vol.51 No.15

By Stephen J. Forman

Four out of five cancer therapies tested in phase III trials do not achieve clinically-meaningful benefit in prolonging survival

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The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty
“We are resolute. We are committed to continuing to move the work forward.”

Trump administration seeks to slash NIH by roughly 40% as 27 institutes and centers are whittled down to eight
NCI to remain intact, but its finances are uncertain; FDA is spared big cuts

RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”
Whistleblowers will be “honored”

TIL + pembro regimen achieves 24% response rate in solid epithelial tumors, marking a step forward in immunotherapy research

What would Mary do?
Trump’s actions call for Lasker-style advocacy

City of Hope’s BMT program performs 20,000th transplant
49-year history creates 20,000 tomorrows

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Four out of five cancer therapies tested in phase III trials do not achieve clinically-meaningful benefit in prolonging survival

YOU MAY BE INTERESTED IN

The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty“We are resolute. We are committed to continuing to move the work forward.”

Trump administration seeks to slash NIH by roughly 40% as 27 institutes and centers are whittled down to eightNCI to remain intact, but its finances are uncertain; FDA is spared big cuts

RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”Whistleblowers will be “honored”

TIL + pembro regimen achieves 24% response rate in solid epithelial tumors, marking a step forward in immunotherapy research

What would Mary do?Trump’s actions call for Lasker-style advocacy

City of Hope’s BMT program performs 20,000th transplant49-year history creates 20,000 tomorrows

Never miss an issue!

Login

The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty
“We are resolute. We are committed to continuing to move the work forward.”

Trump administration seeks to slash NIH by roughly 40% as 27 institutes and centers are whittled down to eight
NCI to remain intact, but its finances are uncertain; FDA is spared big cuts

RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”
Whistleblowers will be “honored”

What would Mary do?
Trump’s actions call for Lasker-style advocacy

City of Hope’s BMT program performs 20,000th transplant
49-year history creates 20,000 tomorrows