Two phase I/II trials that evaluated the safety and efficacy of CD30 CAR-T cell therapy in patients with relapsed/refractory Hodgkin lymphoma showed a high rate of durable complete responses and very favorable safety profile using autologous CD30 CAR-T cell therapy.
Richard Pazdur, founding director of FDA’s Oncology Center of Excellence and long-time FDA visionary, has accepted the top job at FDA’s Center for Drug Evaluation and Research following George F. Tidmarsh’s dramatic ouster from the position.
