The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Genentech’s Entrectinib showed durable response of more than two years NSCLC

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Genentech announced the results for its investigational medicine entrectinib, from an integrated analysis of the pivotal phase II STARTRK-2, phase I STARTRK-1, and phase I ALKA trials, which showed that entrectinib shrank tumors (objective response rate) in 77.4 percent of people with locally advanced or metastatic ROS1-positive non-small cell lung cancer.

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