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Misconduct Expert Dissects Duke Scandal

On Jan. 9, 2015, The Cancer Letter reported that Duke University received information in early 2008 that called into question the validity of the methodology and results published by the Anil Potti research group. Potti, along with his mentor and co-author Joseph Nevins, had galvanized the world of cancer research in 2006 and 2007 with their reports of successful gene expression tests for directing cancer therapy, the “holy grail” of cancer research. The 2008 information came in the form of a letter from a third-year medical student, Brad Perez, who was working in Potti's lab. The letter, which does not seem to have been given any credence at the time, described with precision the problems that eventually resulted in the termination of clinical trials and the subsequent retractions, beginning in 2011, of at least ten (and counting) papers from major scientific journals.
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Robert Cook-Deegan’s Viewers’ Guide To the Super Bowl of Gene Patent Cases 2

Does Myriad have rights to BRCA2?The race to find mutations associated with inherited risk of breast cancer started with Mary-Claire King's announcement of linkage to chromosome 17 in fall 1990. As Kevin Davies documented in his book Breakthrough, it is widely accepted that the team led by Mark Skolnick of the University of Utah and Myriad Genetics won that race to find BRCA1. They cloned and sequenced the gene and identified the first high-risk variants several months ahead of King and other rival groups in the UK, France and the United States. Utah/Myriad filed the first patent applications on BRCA1.