The Cancer Letter

Inside information on cancer research and drug development

Clinical

First extensive immune profiling of sarcomas shows some likely susceptible to immunotherapy

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A study published May 2 in the journal Cancer suggests how both existing and emerging immunotherapy treatments could be successful for sarcomas. Two sarcoma subtypes — leiomyosarcoma and pleomorphic — showed biological characteristics suggesting they are susceptible to an existing immunotherapy approach known as checkpoint inhibitors. This treatment works by blocking a protein that keeps immune cells from attacking cancerous cells.

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