Hegseth orders testosterone testing for troops as FDA moves to loosen TRT prostate cancer warnings Experts caution the move amounts to a “huge, unregulated, natural experiment”

HHS defers more than $1B in Medicaid payments to California, Minnesota pending review of high-risk claims in crackdown on fraud

HHS and the Centers for Medicare & Medicaid Services deferred more than $1 billion in federal Medicaid payments to California and Minnesota as these states submit additional documentation supporting certain Medicaid claims.

HHS joins Trump’s drive to use AI to address chronic disease

HHS has joined President Trump’s “Genesis Mission,” an artificial intelligence platform to harness federal scientific datasets. The purpose of the move is to use AI to further Robert F. Kennedy Jr.’s efforts to end what he calls “the chronic disease crisis,” a focal point of his Make America Healthy Again strategy.

July 24, 2026

Vol.52 No.29

By Claire Marie Porter

Clinical Roundup

USC study shows how pieces of DNA that regulate gene expression drive prostate cancer

A study, which focused on the DNA switches of prostate cancer cells, reveals insights into enhancers that become active during cancer development and turn on genes linked to the disease. The study found that enhancers work cooperatively in 3D networks, rather than as isolated switches. Some enhancers function as “central hubs” that control many genes, while others play a supporting role. These findings could help with the development of targeted cancer therapies.

July 24, 2026

Vol.52 No.29

Drugs & Targets

FDA approves Jideytro for previously treated ROS1-positive non-small cell lung cancer

FDA approved Jideytro (zidesamtinib), a ROS1 selective inhibitor, for the treatment of adult patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer who received a prior ROS1 kinase inhibitor.

July 24, 2026

Vol.52 No.29

Drugs & Targets

FDA grants priority review for Talzenna + Xtandi combo in earlier prostate cancer

FDA accepted for Priority Review a supplemental New Drug Application for Talzenna (talazoparib), an oral poly ADP-ribose polymerase inhibitor, in combination with Xtandi (enzalutamide), an androgen receptor pathway inhibitor, in men with homologous recombination repair gene-altered metastatic castration-sensitive prostate cancer, also known as metastatic hormone-sensitive prostate cancer.

July 24, 2026

Vol.52 No.29

Podcast

How will FDA regulate psychedelics?

FDA has been taking a look at psychedelics as a potential treatment for psychiatric and substance abuse disorders, recently publishing a final guidance for drug sponsors conducting clinical trials of psychedelics, including psilocybin, LSD, and MDMA.

July 22, 2026

Vol.52 No.28

Hegseth orders testosterone testing for troops as FDA moves to loosen TRT prostate cancer warnings

Experts caution the move amounts to a “huge, unregulated, natural experiment”

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HHS defers more than $1B in Medicaid payments to California, Minnesota pending review of high-risk claims in crackdown on fraud

HHS joins Trump’s drive to use AI to address chronic disease

USC study shows how pieces of DNA that regulate gene expression drive prostate cancer

FDA approves Jideytro for previously treated ROS1-positive non-small cell lung cancer

FDA grants priority review for Talzenna + Xtandi combo in earlier prostate cancer

How will FDA regulate psychedelics?

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