MammaPrint + BluePrint genomic profiling predicts anthracycline chemotherapy benefit in HR+HER2- early-stage breast cancer

FDA approves Trodelvy for first-line treatment of mTNBC

FDA approved Trodelvy (sacituzumab govitecan-hziy), a first-in-class Trop-2-directed antibody-drug conjugate, for the first-line treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer.

July 02, 2026

Vol.52 No.26

Clinical Roundup

Neutrophils help triple-negative breast cancer cells spread to other organs, BCM study finds

Researchers at Baylor College of Medicine and collaborating institutions have discovered how immune cells called neutrophils can help triple-negative breast cancer cells metastasize to other organs. The study found these interactions both in animal models and human samples of TNBC.

June 26, 2026

Vol.52 No.25

Clinical Roundup

Camizestrant combination delayed time to first progression by 55% in patients with advanced HR+ breast cancer with ESR1 tumor mutation

Further positive results from the phase III SERENA-6 trial showed camizestrant plus a cyclin-dependent kinase 4/6 inhibitor—palbociclib, ribociclib or abemaciclib—maintained its progression-free survival benefit with longer follow-up and delivered a statistically significant and clinically meaningful improvement in second progression-free survival, demonstrating sustained benefit beyond initial treatment.

June 05, 2026

Vol.52 No.22

Drugs & Targets

FDA approves Enhertu in HER2+ early breast cancer for both neoadjuvant and adjuvant treatment

FDA approved Enhertu (fam-trastuzumab deruxtecan-nxki) for both the neoadjuvant and adjuvant treatment of patients with HER2-positive early breast cancer based on results from the DESTINY-Breast11 and DESTINY-Breast05 Phase III trials, respectively.

May 22, 2026

Vol.52 No.20

Clinical Roundup

Stage 4 breast cancer has increased in incidence and proportion over the last decade

Researchers found that cases of stage 4 breast cancer are increasing both in incidence and as a proportion of all breast cancer diagnoses, according to findings from an observational study.

May 15, 2026

Vol.52 No.19

Drugs & Targets

FDA clears AI digital pathology risk stratification tool in breast cancer

FDA cleared ArteraAI Breast, a multimodal AI-based prognostic and predictive cancer test, for use in patients with early-stage, hormone receptor-positive HER2-negative invasive breast cancer.

May 15, 2026

Vol.52 No.19

MammaPrint + BluePrint genomic profiling predicts anthracycline chemotherapy benefit in HR+HER2- early-stage breast cancer

YOU MAY BE INTERESTED IN

FDA approves Trodelvy for first-line treatment of mTNBC

Neutrophils help triple-negative breast cancer cells spread to other organs, BCM study finds

Camizestrant combination delayed time to first progression by 55% in patients with advanced HR+ breast cancer with ESR1 tumor mutation

FDA approves Enhertu in HER2+ early breast cancer for both neoadjuvant and adjuvant treatment

Stage 4 breast cancer has increased in incidence and proportion over the last decade

FDA clears AI digital pathology risk stratification tool in breast cancer

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