Scientists identify genes that help cancer cells survive in the bloodstream

The Human Tumor Atlas Network charts the roadmap for advancing spatial omics

The NCI Human Tumor Atlas Network (HTAN) has published a cluster of papers intended to advance the framework of spatial omics, the science of profiling morphological and molecular features of human cancers in two and three dimensions.

Stephen Baylin and Andrew Feinberg, of Johns Hopkins, win Technion’s Harvey Prize

Stephen BaylinAndrew FeinbergJohns Hopkins University School of Medicine and Johns Hopkins Kimmel Cancer Center researchers Stephen Baylin and Andrew Feinberg were awarded the 2022–2023 Harvey Prize in the field of Science and Technology by the Technion—Israel Institute of Technology.

December 13, 2024

Vol.50 No.46

Clinical Roundup

Lynparza demonstrates survival benefit in early breast cancer, phase III trial data show

AstraZeneca and Merckannounced long-term results from the OlympiA phase III trial which showed Lynparza (olaparib) demonstrated sustained, clinically meaningful improvements in overall survival, invasive disease-free survival and distant disease-free survival for people with germline BRCA-mutated HER2-negative high-risk early breast cancer.

December 13, 2024

Vol.50 No.46

Clinical Roundup

Imlunestrant improves PFS in breast cancer, phase III data show

Eli Lilly and Co. announced results from the phase III EMBER-3 study of imlunestrant, an investigational, oral selective estrogen receptor degrader, in patients with estrogen receptor positive, human epidermal growth factor receptor 2 negative advanced breast cancer, whose disease progressed on a prior aromatase inhibitor, with or without a CDK4/6 inhibitor.

December 13, 2024

Vol.50 No.46

Clinical Roundup

AI test is equivalent to Oncotype DX at predicting breast cancer recurrence, study shows

COTA Inc., PreciseDx, and Baptist Health South Florida announced study results validating that the artificial intelligence-enabled PreciseBreast test is equivalent to the Oncotype DX test at predicting breast cancer recurrence. The research was presented at the San Antonio Breast Cancer Symposium.

December 13, 2024

Vol.50 No.46

Clinical Roundup

MammaPrint test demonstrates utility in predicting chemotherapy benefit over five years

Agendia Inc. announced it will be presenting new data from the Real-World Data Registry, FLEX, demonstrating MammaPrint’s ability to predict chemotherapy benefit in patients with HR+HER2- early-stage breast cancer. The findings will be presented at the San Antonio Breast Cancer Symposium 2024. The MammaPrint test analyzes the 70 most important genes associated with breast cancer recurrence.

December 13, 2024

Vol.50 No.46

Scientists identify genes that help cancer cells survive in the bloodstream

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The Human Tumor Atlas Network charts the roadmap for advancing spatial omics

Stephen Baylin and Andrew Feinberg, of Johns Hopkins, win Technion’s Harvey Prize

Lynparza demonstrates survival benefit in early breast cancer, phase III trial data show

Imlunestrant improves PFS in breast cancer, phase III data show

AI test is equivalent to Oncotype DX at predicting breast cancer recurrence, study shows

MammaPrint test demonstrates utility in predicting chemotherapy benefit over five years

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