Is gastrectomy indicated?

A study recently published in JAMA suggests lower lifetime gastric cancer risk for CDH1 mutation carriers. Will this lead to changes in management recommendations?

Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on print

A study recently published in JAMA sheds light on cancer risks associated with carrying germline CDH1 mutations, challenging previous, potentially inflated, lifetime cancer risk estimates.  

To access this subscriber-only content please log in or subscribe.

If your institution has a site license, log in with IP-login or register for a sponsored account.*
*Not all site licenses are enrolled in sponsored accounts.

Login Subscribe
Rebecca Sutphen, MD
Co-founder, chief medical officer, InformedDNA
Sue Friedman
Executive director, founder, FORCE (Facing Hereditary Cancer Empowered)
Jon Florin
Executive director, chief patient advocate, No Stomach for Cancer
Table of Contents

YOU MAY BE INTERESTED IN

Breast, bladder, and pancreatic cancers are increasingly being treated with a broad range of therapies before a patient undergoes surgery, and cancer stage at diagnosis continues to be a leading factor in determining a person’s survival rate for all types of cancer, according to the first-ever annual cancer report from the National Cancer Database.
FDA has approved Vyloy (zolbetuximab-clzb), a claudin 18.2-directed cytolytic antibody, with fluoropyrimidine- and platinum-containing chemotherapy, for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction adenocarcinoma whose tumors are CLDN18.2 positive, as determined by an FDA-approved test.
Rebecca Sutphen, MD
Co-founder, chief medical officer, InformedDNA
Sue Friedman
Executive director, founder, FORCE (Facing Hereditary Cancer Empowered)
Jon Florin
Executive director, chief patient advocate, No Stomach for Cancer

Never miss an issue!

Get alerts for our award-winning coverage in your inbox.

Login