Epigeneticists may be looking for epigenome-disease associations in the wrong place

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

New research on the possibility to kill TNBCs by hijacking signals that normally drive mammary gland involution was released in Nature.

October 11, 2024

Vol.50 No.38

Tumors are able to form with no DNA mutations, fly study shows

Tumors are able to form without any DNA mutations, according to a recent proof-of-principle study performed in flies. Epigenetic changes alone—even temporary alterations—induced permanent cancer cell fate.

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

A study published in Nature reveals the functional relevance of tumor-neuron interactions that regulate the growth of ependymoma brain tumors.

August 02, 2024

Vol.50 No.31

Clinical Roundup

Unexpected role of OTX2 drives aggressive medulloblastoma

Researchers at Baylor College of Medicine, Texas Children’s Hospital, the University of Manitoba, and collaborating institutions revealed an unexpected way in which the protein OTX2 drives the progression of medulloblastoma—the most common aggressive childhood brain cancer.

July 19, 2024

Vol.50 No.29

Clinical Roundup

Pan-cancer proteogenomics reveals potential drug targets

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets.

June 28, 2024

Vol.50 No.26

Clinical Roundup

Upregulating TERT gene expression reverses multiple hallmarks of aging

Researchers at MD Anderson Cancer Center have demonstrated that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

June 28, 2024

Vol.50 No.26

Epigeneticists may be looking for epigenome-disease associations in the wrong place

YOU MAY BE INTERESTED IN

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution

Tumors are able to form with no DNA mutations, fly study shows

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

Unexpected role of OTX2 drives aggressive medulloblastoma

Pan-cancer proteogenomics reveals potential drug targets

Upregulating TERT gene expression reverses multiple hallmarks of aging

Renew today!

Subscriber content

Login