In Brief

MD Anderson to advance cancer prevention, treatment, research and education in Mozambique and Brazil

The University of Texas MD Anderson Cancer Center plans to expand its global oncology efforts in Mozambique and Brazil, including a new four-year agreement to broaden existing cancer prevention and treatment efforts with the Ministry of Health in Mozambique and a $5.1 million grant from NIH focused on cervical cancer prevention and treatment among women living with the human immunodeficiency virus.
Clinical Roundup

Phase I MD Anderson study shows YAP/TEAD inhibitor VT3989 is well tolerated and shows antitumor activity in advanced mesothelioma and NF2-mutant cancers

The first-in-class YAP/TEAD inhibitor VT3989 was well tolerated with durable antitumor responses in patients with advanced malignant mesothelioma and other tumors with NF2 mutations, according to results of a phase I trial led by researchers at MD Anderson Cancer Center. The first-in-human study was presented today at the 2023 American Association for Cancer Research annual meeting.
Clinical Roundup

MD Anderson research: combination therapies for BRAF V600E mutations, cancer biomarkers in extracellular vesicles, and strategies for overcoming treatment resistance in lung cancer and AML

MD Anderson Cancer Center researchers have identified recent developments in effective combination therapies for patients with BRAF V600E mutations, an approach to identify cancer biomarkers in extracellular vesicles, therapeutic strategies for improving treatment responses in non-small cell lung cancer, and a novel combination therapy to overcome treatment resistance in a subset of patients with acute myeloid leukemia.