Vol.

No.

July 28, 2023Jul 28, 2023

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Cover Story

Clinical

Carolyn Bertozzi focused on bioorthogonal chemistry in 1996 and won the Nobel Prize in 2022

This is how her discovery got to cancer clinical trials

By Jacquelyn Cobb

In 1996, Carolyn Bertozzi and her lab at UC Berkeley were working to develop a way to image cell-surface glycans: sugar-based macromolecules that coat the surface of cells.

Clinical Conversation with The Cancer Letter

Nobel Prize-winning technology may enable delivery of up to 12x the standard doxorubicin dose

By Jacquelyn Cobb

NCI

Bertagnolli: Drug shortages, potential NCI budget cuts strain the already-stressed system

By Matthew Bin Han Ong

Free In the Archives

Cancer History Project book spotlight: Cancer Crusade

In Brief

Irwin H. Krakoff, pioneering oncologist, turns 100

Tracy Crane, Janice Lu, David Mutch, William Small Jr. named to NRG Oncology leadership positions

Walter J. Curran receives first NRG Oncology Gold Medal Award

Jonathan E. Rosenberg, Matthew Galsky named co-chairs of Alliance Genitourinary Committee

American Oncology Network, in partnership with Thyme Care, participates in the Enhancing Oncology Model

MUSC Hollings’s Raymond N. DuBois inducted as a fellow into the Royal College of Physicians

Karen Mustian named associate director for population science at University of Rochester Wilmot Cancer Institute

Paulo Rodriguez named chair of the Department of Immunology and co-leader of the Immuno-Oncology Program at Moffitt

Moffitt opens Moffitt McKinley Hospital

Martin Edelman appointed inaugural chair of the Department of Medical Oncology at Temple

Sukhmani K. Padda named professor, vice chair of medical oncology at Fox Chase

Lali Medina-Kauwe named inaugural chair in medical discovery at Cedars-Sinai

Niki Patel named hematologist, oncologist at Cedars-Sinai

MD Anderson to advance cancer prevention, treatment, research and education in Mozambique and Brazil

Wistar receives $12M NCI grant to investigate link between Epstein-Barr Virus and carcinomas

UPenn’s Saar Gill receives $300,000 to develop genetically engineered stem cell products to fight gastroesophageal cancer

Clinical Roundup

Maintenance therapy with Xpovio may extend PFS in some endometrial cancers

Phase III ATLAS, ENVISION clinical trials meet primary endpoints

Screening will not solve racial disparities in melanoma outcomes, study suggests

Study investigates cancer among people experiencing homelessness to form basis for prevention program

USC study finds unexpected mechanism of cancer metastasis

GEMINI blood test developed by Hopkins researchers could allow earlier detection of lung, other cancers

Loss of tumor suppressor gene portends poor prognosis in brain tumors, study finds

CAR T-cell innovation could pave the way for less toxic therapy for multiple myeloma

Moderna, Merck initiate phase III trial evaluating V940 + Keytruda in melanoma indication

MD Anderson study: Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance

RNA-based therapy combats melanoma in mouse models

Drugs & Targets

Keytruda + trastuzumab + chemo receive positive CHMP opinion for first-line HER2+ gastric cancer

Opdivo receives positive CHMP opinion for early stage melanoma

Tepkinly receives positive CHMP opinion for R/R DLBCL

MD Anderson, Nexo Therapeutics collaborate to advance therapies against intractable targets

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Carolyn Bertozzi focused on bioorthogonal chemistry in 1996 and won the Nobel Prize in 2022

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