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In Brief

GRAIL announces retirement of CEO Bob Ragusa, appoints President Josh Ofman as successor

March 13, 2026
Vol.52 No.10
One result, two reactions: GRAIL’s Hall and NCI’s Castle react to negative NHS-Galleri trial outcome
Podcast

One result, two reactions: GRAIL’s Hall and NCI’s Castle react to negative NHS-Galleri trial outcome

March 11, 2026
GRAIL presses on with Galleri test despite missed primary endpoint in pivotal study
News Analysis

GRAIL presses on with Galleri test despite missed primary endpoint in pivotal study
Where GRAIL sees signals of benefit in the subgroups, screening experts see signs of overdiagnosis

March 06, 2026
Vol.52 No.09
By Jacquelyn Cobb and Sara Willa Ernst
GRAIL’s Megan Hall: “I think we can be confident that there is clinical benefit to implementing this technology. And I think that’s really hard to argue with.”
Conversation with The Cancer Letter

GRAIL’s Megan Hall: “I think we can be confident that there is clinical benefit to implementing this technology. And I think that’s really hard to argue with.”
Mainstream epidemiologists beg to differ

March 06, 2026
Vol.52 No.09
By Jacquelyn Cobb and Sara Willa Ernst
NCI’s Philip Castle on NHS-Galleri results: “I’m sorry that it didn’t work, but it keeps the national conversation going.”
Conversation with The Cancer Letter

NCI’s Philip Castle on NHS-Galleri results: “I’m sorry that it didn’t work, but it keeps the national conversation going.”
Castle is “disappointed” by Galleri results but not discouraged by implications for MCDs

March 06, 2026
Vol.52 No.09
By Jacquelyn Cobb and Sara Willa Ernst
Clinical Roundup

NHS-Galleri MCD trial fails to meet primary endpoint of stage shift

February 27, 2026
Vol.52 No.08
By Sara Willa Ernst
Super Bowl ad by Hims & Hers features GRAIL’s Galleri MCD test
Cancer Policy

Super Bowl ad by Hims & Hers features GRAIL’s Galleri MCD test

February 13, 2026
Vol.52 No.06
By Jacquelyn Cobb and Sara Willa Ernst
Class action complaint alleging GRAIL insider fraud resubmitted after dismissal

Class action complaint alleging GRAIL insider fraud resubmitted after dismissal

October 31, 2025
Vol.51 No.40
By Jacquelyn Cobb
Early endpoints are a balance of risk and benefit
Podcast

Early endpoints are a balance of risk and benefit

October 29, 2025
Vol.51 No.39
GRAIL’s woes raise questions about the prospects of MCDs and standards for their evaluation

GRAIL’s woes raise questions about the prospects of MCDs and standards for their evaluation

October 25, 2024
Vol.50 No.40
By Jacquelyn Cobb

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