NCI Trials for May 2020

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The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month.

For further information, contact the principal investigator listed.


Phase II – A071702

A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma

Alliance for Clinical Trials in Oncology

Dunn, Gavin Peter

(314) 747-6141


Phase II – EAQ191

Cancer Therapy Risk-Reduction with Intensive Systolic BP Management (CARISMA) – a Phase II Study

ECOG-ACRIN Cancer Research Group

Ky, Bonnie

(215) 573-6606


Phase II – S1905

A Phase II Study of AKR1C3-Activated Prodrug OBI-3424 (OBI-3424) In Patients with Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)

SWOG

Advani, Anjali S.

(216) 445-9354


Phase III – EA5181

Randomized Phase III Trial of MEDI4736 (Durvalumab) as Concurrent and Consolidative Therapy or Consolidative Therapy Alone for Unresectable Stage 3 NSCLC

ECOG-ACRIN Cancer Research Group

Pennell, Nathan Adam

(216) 445-9282

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In an effort to target the right patients, genetic screening is becoming more common in clinical trials. But incorporating it can be complex and add a significant burden for both patients and clinical trial sites. Genetic counseling can streamline that process and help drug and gene therapy developers expedite the recruitment of genetically-eligible participants for their trials and use genetic testing results to accelerate the speed and success of clinical trials.

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