FDA grants Priority Review for Seattle Genetics agent tucatinib

FDA, NCI align to simplify clinical research, producing a model “pragmatic” registration trial in NSCLC

Pragmatica-Lung is shaping up as the clinical trial to watch—not just because of the research question, but because of the way it’s being addressed.

December 02, 2022

Vol.48 No.43

By Jacquelyn Cobb, Matthew Bin Han Ong and Paul Goldberg

Conversation with The Cancer Letter

Roy Herbst: I hope Pragmatica-Lung will become the norm

Pragmatica-Lung is the first of what is likely to be a series of simpler trials with relaxed enrollment criteria and streamlined data collection requirements.

December 02, 2022

Vol.48 No.43

By Jacquelyn Cobb and Paul Goldberg

Conversation with The Cancer Letter

Ellen Sigal: Pragmatica-Lung may be a model for other trials that are unnecessarily complex

The Pragmatica-Lung trial required many people to start to think differently about conducting phase III clinical trials—and it took a lot of advocacy to make the trial launch quickly, said Ellen Sigal, founder and chair of Friends of Cancer Research.

December 02, 2022

Vol.48 No.43

By Matthew Bin Han Ong

Obituary

UNC’s Jo Anne Earp, behavioral scientist and civil rights activist, dies at 79

Dr. Jo Anne L. Earp, 79, professor emerita and past chair in the Department of Health Behavior at the UNC Gillings School of Global Public Health, passed away in the early hours of Nov. 18 at UNC Hospitals in Chapel Hill, NC.

Podcasts, panels, and archives of the first NCI-designated cancer centers

Can you name the first NCI-designated cancer centers? The answer to this question is anything but straightforward—in part because the contenders predate NCI’s definition of a “cancer center”.

December 02, 2022

Vol.48 No.43