The Cancer Letter

Inside information on cancer research and drug development

Drugs & Targets

FDA grants orphan designations to Debio 1143 and SUBA-Itraconazole Capsules

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FDA granted Orphan Drug Designation to Debio 1143 for the treatment of ovarian cancer. Debio 1143 is an oral, small molecule inhibitor with a dual pro-apoptotic and immunomodulatory mode of action developed as a chemo/radio-sensitizer, according to Debiopharm International SA, the drug’s sponsor. Debiopharm plans to expand the clinical development of this therapy to patients...

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