The Cancer Letter

Inside information on cancer research and drug development

Drugs & Targets

AbbVie and CytomX Therapeutics to collaborate on probody drug conjugates

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AbbVie and CytomX Therapeutics Inc. entered into a collaboration to co-develop Probody Drug Conjugates against CD71, also known as transferrin receptor 1 (TfR1). Probody therapeutics are designed to take advantage of conditions in the tumor microenvironment to enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues. Under the agreement, CytomX...

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