FDA granted orphan drug designation to the WT1 cancer vaccine developed by SELLAS Life Sciences Group for the treatment of patients with malignant pleural mesothelioma. SELLAS recently reported positive results of a phase II trial of its WT1 vaccine in MPM patients, showing that overall survival improved and progression-free survival doubled. Based on these findings,...
A group of melanoma experts, joined by three advocacy groups focused on melanoma, has engaged FDA in a public discussion of the challenges of developing new drugs in the refractory setting and the role crossover can play in such trials.
