AstraZeneca and Heptares Therapeutics enter licensing agreement

AstraZeneca and Heptares Therapeutics entered into a licensing agreement under which AstraZeneca will acquire exclusive global rights to develop, manufacture and commercialize the adenosine A2A receptor antagonist HTL-1071, a small molecule immuno-oncology candidate.

AstraZeneca will focus on exploring HTL-1071 and any additional compounds across a range of cancers, including in combination with its existing portfolio of immunotherapies.

The companies will also collaborate to discover further A2A receptor-blocking compounds for development in cancer immunotherapy.

Heptares will receive an upfront payment of $10 million and is eligible to receive additional milestone payments based on agreed pre-clinical and clinical events. Subject to successful completion of development and commercialization milestones, Heptares is also eligible to receive more than $500 million as well as royalty payments.

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AstraZeneca and Heptares Therapeutics enter licensing agreement

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AstraZeneca and Heptares Therapeutics enter licensing agreement

YOU MAY BE INTERESTED IN

In The Headlines: Are cancer registries on the chopping block, and what does it mean if they are?

Steven Libutti tells us about building a $900 million cancer hospital for Rutgers RWJBarnabas Health

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Makary vows to speed up drug approvals and end FDA’s “cozy” relationship with industryCommissioner promises to protect scientific integrity while bringing in “fresh” MAHA ideas

Ci4CC’s 23rd Cancer Center Summit to focus on accelerating oncology innovation through AI

Advancing peritoneal oncology: Innovations in surgical strategies and research

Never miss an issue!

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Makary vows to speed up drug approvals and end FDA’s “cozy” relationship with industry
Commissioner promises to protect scientific integrity while bringing in “fresh” MAHA ideas