H. Kim Lyerly

H. Kim Lyerly, MD

Member, Board of directors, Accelerating Anticancer Agent Development and Validation Workshop Foundation; George Barth Geller Professor of Cancer Research, Professor of surgery, Duke University School of Medicine

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FreeGuest Editorial
At the 2026 Annual Meeting of the American Society of Clinical Oncology in Chicago, results from the phase III HARMONi-6 trial were presented at the plenary session and published simultaneously in The Lancet. The HARMONi-6 trial tested a novel bispecific antibody that engages PD-1 and VEGF (ivonescimab), given with platinum-doublet chemotherapy to patients with previously untreated advanced squamous non-small cell lung cancer. 
Guest Editorial
Globally, about 18 million people will be diagnosed with cancer and approximately 10 million people will die from cancer this year. Between 30–50% of these cancer cases are potentially preventable today, a fact that highlights that prevention remains one of the most effective and cost-effective long-term strategies to reduce the global cancer burden. 

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