Phase III Jakavi Trial in Polycythemia Vera Demonstrates Control Without Phlebotomy

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A phase III clinical trial demonstrated Jakavi (ruxolitinib) significantly improved hematocrit control without the need for phlebotomy and reduced spleen size in patients with polycythemia vera who had an inadequate response to or unacceptable side effects from hydroxyurea, as defined according to the modified European LeukemiaNet criteria.

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Vinay Prasad, a MAHA-aligned hematologist-oncologist with an avid cyber following, was named director of the FDA Center for Biologics Evaluation and Research, where he will be responsible for the agency’s regulation of vaccines and biologics, including cell and gene therapies.

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