NCI CTEP-Approved Trials for the Month of May

The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.

Phase II

9543: A Phase 2 Study to Determine the Efficacy of the BTK Inhibitor Ibrutinib (PCI-32765) in Patients with Relapsed or Refractory Precursor-B Lymphoblastic Leukemia (B-ALL). MD Anderson Cancer Center; Burger, Jan A. (713) 792-1865

AMC-089: A Phase II Study of Gamma Secretase Inhibitor PF-03084014 in Patients with AIDS-Associated Kaposi Sarcoma. AIDS-Associated Malignancies Clinical Trials Consortium; Ratner, Lee. (314) 362-8836

CITN-07-FLT3L: A Phase II, Open-Label, Multicenter, Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with Malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant Human Flt3 Ligand. Cancer Immunotherapy Trials Network; Bhardwaj, Nina. (212) 263-5814

Phase Other

AALL14B1-Q: Deep Sequencing for Minimal Residual Disease Detection in Acute Lymphoblastic Leukemia ALL. Children’s Oncology Group; Wood, Brent Lee. (206) 288-7115

AAML14B4-Q: Role of EVI-1 Hyperexpression in Pediatric and Young Adult Acute Myeloid Leukemia. Children’s Oncology Group; Qian, Zhijian. (312) 355-3295

EA914LT1: Lab Testing of AML Patient Samples. ECOG-ACRIN Cancer Research Group; Wald, David. (216) 368-5668

S0016B: Use of Chromosome Genomic Microarray Testing (CGAT) to Identify Novel Genetic Aberrations Impacting Patient Outcome in S0016 Follicular Lymphoma Patients. SWOG; Fang, Min (206) 288-1385

Pilot Phase

ABTC-1301: Pilot Study of MLN0128 in Preoperative Recurrent Glioblastoma (GBM) Patients. Adult Brain Tumor Consortium; Lee, Eudocia Quant. (617) 632-2166

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NCI CTEP-Approved Trials for the Month of May

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The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woes
Directors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheaval
Susan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times
“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosis
Observational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms

Insights from ASCO 2025: Real-world evidence drives clinical decision-making

The Cancer Letter receives nine journalism, design awards

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NCI CTEP-Approved Trials for the Month of May

YOU MAY BE INTERESTED IN

The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woesDirectors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheavalSusan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosisObservational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms

Insights from ASCO 2025: Real-world evidence drives clinical decision-making

The Cancer Letter receives nine journalism, design awards

Never miss an issue!

Login

The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woes
Directors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheaval
Susan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times
“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosis
Observational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms